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Home >> Publications >> Difference in absolute CD4+ count according to CD4 percentage between Asian and Caucasian HIV-infected patients.

Publication

Author(s):

Achhra AC, Zhou J, Dabis F, Pujari S, Thiebaut R, Law MG, Bonnet F.

Pub Title:

Difference in absolute CD4+ count according to CD4 percentage between Asian and Caucasian HIV-infected patients.

Pub Date:

Oct 8 2010

Pub Region(s):

Asia-Pacific

Journal Issue:

1

Page Number:
1/4/2013

Journal:

Title: 
Journal of AIDS and Clinical Research
Link: 
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071513/

PubMed: 21479149
Pub PDF: PDF icon 21479149.pdf

Abstract
We compared the absolute CD4+ count, at different CD4+ percentages (CD4%), between Asian (n=442) and Caucasian (n=674) untreated HIV-infected individuals, using linear regression methods. At any given CD4%, Asians had lower CD4+ count than Caucasians (p=0.001). The difference varied from 38.9 cells/mm(3) (95% CI: 3.3-74.5 cells/mm(3)) at CD4% of 15% to 108.7 cells/mm(3) (95% CI: 42.5-174.9 cells/mm(3)) at CD4% of 40%. The impact of these differences on prognosis is uncertain, but it may be that the prognostic thresholds for CD4+ count used in Caucasian populations are inappropriate in Asian populations.

PMID: 21479149 [PubMed]

PMCID: PMC3071513

 

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Citation:

Achhra AC, Zhou J, Dabis F, Pujari S, Thiebaut R, Law MG, Bonnet F. Difference in absolute CD4+ count according to CD4 percentage between Asian and Caucasian HIV-infected patients. J AIDS Clin Res. 2010 Oct 8;1(1):1-4. PubMed PMID: 21479149; PubMed Central PMCID: PMC3071513.