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Home >> Publications >> Effect of HIV infection on body composition and fat distribution in Rwandan women.

Publication

Author(s):

Mutimura E1, Anastos K, Zheng Lin, Cohen M, Binagwaho A, Kotler DP.

Pub Title:

Effect of HIV infection on body composition and fat distribution in Rwandan women.

Pub Date:

Jun 9 2015

Pub Region(s):

Central Africa

Journal Issue:

May/June

Page Number:
173-178

Journal:

Title: 
Journal of the International Association of Physicians in AIDS Care
Link: 
http://jia.sagepub.com/content/9/3/173.long

PubMed: 20530472
Pub PDF:

OBJECTIVE:

To assess the association of HIV infection with body weight and composition in Rwandan women.

DESIGN:

Body weight and composition, the latter determined by bioelectrical impedance analysis (BIA) and by anthropometry, were compared in 620 HIV-positive and 211 HIV-negative participants. Associations of HIV with body composition were assessed, and t tests compared the groups.

RESULTS:

HIV-positive women were younger (-7.0 years, P < .001) and shorter (-2.1 cm, P < .001). Mean body weight, body mass index (BMI), total body fat, and waist-to-hip ratio (WHR) were similar. Mean fat-free mass was 2.5% greater in HIV-negative participants, and 19% of HIV-positive group had BMI <18.5 kg/m(2) versus 26% of the HIV-negative group (P < .05). CD4 counts and body composition were not associated.

CONCLUSIONS:

Malnutrition was common in this cohort of Rwandan women. However, HIV infection was not associated with nutritional status. Factors other than malnutrition may influence quality-of-life outcomes in HIV-infected Rwandan women. Initiatives to improve nutritional status should be population-wide and not restricted to the HIV-infected population.

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Citation:

Mutimura E, Anastos K, Zheng Lin, Cohen M, Binagwaho A, Kotler DP. Effect of HIV infection on body composition and fat distribution in Rwandan women. J Int Assoc Physicians AIDS Care (Chic). 2010 May-Jun;9(3):173-8. doi: 10.1177/1545109710366472. PubMed PMID: 20530472; PubMed Central PMCID: PMC4460979.