LOGIN

International Epidemiology Databases to Evaluate AIDS

Home >> Publications >> Immune recovery after starting ART in HIV-infected patients presenting and not presenting with tuberculosis in South Africa.

Publication

Author(s):

Schomaker M, Egger M, Maskew M, Garone D, Prozesky H, Hoffmann CJ, Boulle A, Fenner L; IeDEA Southern Africa.

Pub Title:

Immune recovery after starting ART in HIV-infected patients presenting and not presenting with tuberculosis in South Africa.

Pub Date:

May 1 2013

Pub Region(s):

Southern Africa

Journal Issue:

1

Page Number:
142-5

Journal:

Title: 
JAIDS- Journal of Acquired Immune Deficiency Syndromes
Link: 
http://journals.lww.com/jaids/pages/articleviewer.aspx?year=2013&issue=05010&article=00021&type=abstract

PubMed: 23364513
Pub PDF: PDF icon 23364513.pdf

Abstract
We studied the immune response after starting antiretroviral treatment (ART) in 15,646 HIV-infected patients with or without tuberculosis (TB) at presentation in 3 ART programs in South Africa between 2003 and 2010. Patients presenting with TB had similar increases in CD4 cells compared with all other patients (adjusted difference 4.9 cells/µL per 6 months, 95% confidence interval: 0.2 to 9.7). Younger age, advanced clinical stage, female sex, and lower CD4 cell count at ART start were all associated with steeper CD4 slopes. In South Africa, HIV-infected patients presenting with TB experience immune recovery after starting ART that is no worse than in other patients.

PMID: 23364513 [PubMed - indexed for MEDLINE]

PMCID: PMC3671097 [Available on 2014/5/1]

 

The following websites provide guidelines and policies when citing from PubMed®: http://www.ncbi.nlm.nih.gov/books/NBK7243/
http://www.nlm.nih.gov/bsd/policy/cit_format.html

Citation:

Schomaker M, Egger M, Maskew M, Garone D, Prozesky H, Hoffmann CJ, Boulle A, Fenner L; IeDEA Southern Africa. Immune recovery after starting ART in HIV-infected patients presenting and not presenting with tuberculosis in South Africa. J Acquir Immune Defic Syndr. 2013 May 1;63(1):142-5. doi: 10.1097/QAI.0b013e318288b39d. PubMed PMID: 23364513; PubMed Central PMCID: PMC3671097.